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Associations between adolescent cannabis use and neuropsychological decline: a longitudinal co-twin control study

This originally appeared at https://onlinelibrary.wiley.com/doi/abs/10.1111/add.13946 Madeline H. Meier, Avshalom Caspi, Andrea Danese, Helen L. Fisher, Renate Houts, Louise Arseneault, Terrie E. Moffitt First published: 22 July 2017 https://doi.org/10.1111/add.13946 Abstract Aims This study tested whether adolescents who used cannabis or met criteria for cannabis dependence showed neuropsychological impairment prior to cannabis initiation and neuropsychological decline from before to after cannabis initiation. Design […]

Evaluating the impact of cannabinoids on sleep health and pain in patients with chronic neuropathic pain

This originally appeared at https://pubmed.ncbi.nlm.nih.gov/36598058/ Evaluating the impact of cannabinoids on sleep health and pain in patients with chronic neuropathic pain: a systematic review and meta-analysis of randomized controlled trials Aidan Leonard McParland  1 , Anuj Bhatia  2   3 , John Matelski  4 , Chenchen Tian  3 , Calvin Diep  3 , Hance Clarke  2   3 , Daniel Kapustin  […]

The medicinal use of cannabis and cannabinoids–an international cross-sectional survey on administration forms

This originally appeared at https://pubmed.ncbi.nlm.nih.gov/24175484/ Abstract Cannabinoids, including tetrahydrocannabinol and cannabidiol, are the most important active constituents of the cannabis plant. Over recent years, cannabinoid-based medicines (CBMs) have become increasingly available to patients in many countries, both as pharmaceutical products and as herbal cannabis (marijuana). While there seems to be a demand for multiple cannabinoid-based […]

Low Dose Vaporized Cannabis Significantly Improves Neuropathic Pain

This originally appeared at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566631/ Published online 2012 Dec 11. doi: 10.1016/j.jpain.2012.10.009 PMCID: PMC3566631 NIHMSID: NIHMS439212 PMID: 23237736 Barth Wilsey, MD, Thomas D. Marcotte, PhD, Associate Professor, Reena Deutsch, PhD, Statistician, Ben Gouaux, Research Associate, Staci Sakai, Research Associate, and Haylee Donaghe, Research Associate Abstract We conducted a double-blind, placebo-controlled, crossover study evaluating the analgesic efficacy of vaporized cannabis in subjects, the majority of whom were experiencing neuropathic pain despite […]

The effect of cannabis on regular cannabis consumers’ ability to ride a bicycle

This originally appeared at https://link.springer.com/article/10.1007/s00414-015-1307-y 15 December 2015 Abstract To assess the effects of cannabis on the ability required to ride a bicycle, repetitive practical cycling tests and medical examinations were carried out before and after inhalative consumption of cannabis. A maximum of three joints with body weight-adapted THC content (300 μg THC per kg body […]

A Longitudinal Comparison of Persistent Cannabis vs Tobacco Users

This article originally appeared at https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2526003 Associations Between Cannabis Use and Physical Health Problems in Early Midlife A Longitudinal Comparison of Persistent Cannabis vs Tobacco Users Madeline H. Meier, PhD1; Avshalom Caspi, PhD2,3,4; Magdalena Cerdá, DrPH5; et alRobert J. Hancox, MD6; HonaLee Harrington, BA2,3; Renate Houts, PhD2,3; Richie Poulton, PhD7; Sandhya Ramrakha, PhD7; W. Murray Thomson, PhD8; Terrie E. Moffitt, PhD2,3,4 JAMA Psychiatry. 2016;73(7):731-740. doi:10.1001/jamapsychiatry.2016.0637 Abstract Importance  After major policy changes in the United States, policymakers, health care professionals, and the general public seek information about […]

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

This article originally appeared at https://www.pnas.org/doi/full/10.1073/pnas.160105897 Authors: A. M. Malfait, R. Gallily, P. F. Sumariwalla, +3, and M. FeldmannAuthors Info & Affiliations August 1, 2000 https://doi.org/10.1073/pnas.160105897 Abstract The therapeutic potential of cannabidiol (CBD), the major nonpsychoactive component of cannabis, was explored in murine collagen-induced arthritis (CIA). CIA was elicited by immunizing DBA/1 mice with type II collagen (CII) in complete Freund’s adjuvant. The […]

Rates and correlates of cannabis-associated psychotic symptoms in over 230,000 people who use cannabis

This article originally appeared at https://www.nature.com/articles/s41398-022-02112-8 Authors: Translational Psychiatry volume 12, Article number: 369 (2022) Abstract Cannabis, a widely used psychoactive substance, can trigger acute cannabis-associated psychotic symptoms (CAPS) in people who use cannabis (PWUC). To assess rates and correlates of CAPS requiring emergency medical treatment, we analyzed data from an international sample of PWUC (n = 233,475). We found […]

Can Cannabis be Considered a Substitute Medication for Alcohol?

This article originally appeared at https://pubmed.ncbi.nlm.nih.gov/24402247/ Author: Meenakshi Sabina Subbaraman* Alcohol Research Group, Emeryville, CA 94608, USA *Corresponding author: Alcohol Research Group, 6475 Christie Ave, Suite 400, Emeryville, CA 94608, USA. Tel.: +1-510-597-3440; Fax: +1-510-985-6459; E-mail: [email protected](Received 3 July 2013; first review notified 12 August 2012; in revised form 3 December 2013; accepted 6 December […]

Cannabis as a substitute for alcohol and other drugs

This article originally appeared at https://harmreductionjournal.biomedcentral.com/articles/10.1186/1477-7517-6-35 Author Amanda Reiman1  Harm Reduction Journal volume 6, Article number: 35 (2009) Abstract Background Substitution can be operationalized as the conscious choice to use one drug (legal or illicit) instead of, or in conjunction with, another due to issues such as: perceived safety; level of addiction potential; effectiveness in relieving symptoms; access […]