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Is Marijuana Addictive? It Depends How You Define Addiction

This originally appeared at https://healthland.time.com/2010/10/19/is-marijuana-addictive-it-depends-how-you-define-addiction/ Does marijuana cause addiction? As Californians prepare to vote on Prop 19 — which would legalize recreational use of the drug, at least under state law — the question is more pertinent than ever. The answer, however, is less than clear: addiction experts tend to agree that pot is addictive, […]

Long-term behavioral and biochemical effects of an ultra-low dose of D9-tetrahydrocannabinol (THC) neuroprotection and ERK signaling

This article originally appeared at https://link.springer.com/article/10.1007/s00221-012-3186-5 Abstract We have previously reported that a singleinjection of an ultra-low dose of delta-9-tetrahydrocanna-binol (THC; the psychoactive ingredient of marijuana)protected the brain from pentylenentetrazole (PTZ)-induced cognitive deficits when applied 1–7 days before or1–3 days after the insult. In the present study we expandedthe protective profile of THC by showing […]

Comparative risk assessment of alcohol,tobacco, cannabis and other illicit drugs using the margin of exposure approach

This originally appeared at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311234/pdf/srep08126.pdf A comparative risk assessment of drugs including alcohol and tobacco using the margin of exposure (MOE)approach was conducted. The MOE is defined as ratio between toxicological threshold (benchmark dose)and estimated human intake. Median lethal dose values from animal experiments were used to derive thebenchmark dose. The human intake was calculated […]

Exploring cannabis use by patients with multiple sclerosis in a state where cannabis is legal

Laura Weinkle M.S. , Christopher H. Domen Ph.D. , Ian Shelton B.A. ,Stefan Sillau Ph.D. , Kavita Nair Ph.D. , Enrique Alvarez M.D., Ph.D. , Exploring cannabis use by pa-tients with multiple sclerosis in a state where cannabis is legal, Multiple Sclerosis and Related Disorders(2018), doi: https://doi.org/10.1016/j.msard.2018.11.022 Highlights: 38% percent of Multiple Sclerosis patients surveyed […]

Marijuana Dependence and Its Treatment

Abstract The prevalence of marijuana abuse and dependence disorders has been increasing among adults and adolescents in the United States. This paper reviews the problems associated with marijuana use, including unique characteristics of marijuana dependence, and the results of laboratory research and treatment trials to date. It also discusses limitations of current knowledge and potential […]

Why you shouldn’t dismiss the risk of marijuana addiction

There are real concerns with marijuana addiction. That doesn’t mean legalization is a bad idea. It is now widely accepted that marijuana is, at the very least, less dangerous than other recreational drugs. The typical line you’ll hear — I certainly do in my email inbox — is that “marijuana is harmless,” often meant as […]

Can Marijuana Ease the Opioid Epidemic?

NEW YORK — After a 12-year battle with debilitating abdominal conditions that forced her to stop working, marijuana has helped Lynn Sabulski feel well enough to look for a job. Sabulski is among nearly 14,000 patients in New York state who are certified to use medical marijuana for one of 10 conditions, including her primary […]

Can this man successfully treat opioid addiction with marijuana?

hen Joe Schrank got the call six years ago that his friend Greg Giraldo had been found unconscious after an overdose in a New Jersey hotel room, he was not surprised. Giraldo, a comedian, had cycled through the addiction loop for years, and Schrank had tried in vain to save him. “Greg’s death really rattled […]

Is it really beneficial to take some time off from the herb?

Everything You Need To Know About Weed Tolerance Breaks Is it really beneficial to take some time off from the herb? Have you been spending a lot of money on weed, lately? If you’re a regular herbivore, chances are you have a fairly high tolerance for THC. While researchers have yet to reach a verdict […]