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Neurodevelopmental outcomes in children after prenatal marijuana exposure

This article originally appeared at https://pubmed.ncbi.nlm.nih.gov/37283466/ Authors Oliver G Isik  1 , Ling Guo  1 , Andrew J O Whitehouse  2 , Guohua Li  1   3 , Caleb Ing  1   3 Abstract Background: The effect of prenatal marijuana exposure (PME) on child neurodevelopment remains poorly understood. Prior studies have demonstrated inconsistent results. Objectives: This study evaluated the […]

Prevention of Alzheimer’s Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation

This article originally appeared at https://www.jneurosci.org/content/25/8/1904.abstract Authors: Belén G. Ramírez, Cristina Blázquez, Teresa Gómez del Pulgar, Manuel Guzmán and María L. de Ceballos Journal of Neuroscience 23 February 2005, 25 (8) 1904-1913; DOI: https://doi.org/10.1523/JNEUROSCI.4540-04.2005 Abstract Alzheimer’s disease (AD) is characterized by enhanced β-amyloid peptide (βA) deposition along with glial activation in senile plaques, selective neuronal loss, and cognitive deficits. Cannabinoids are neuroprotective agents against excitotoxicity in […]

CHRONIC ADMINISTRATION OF CANNABIDIOL TO HEALTHY VOLUNTEERS AND EPILEPTIC PATIENTS

Pharmacology 21: 175-185 (1980) Jomar M. Cunha, E.A. Carlini, Aparecido E. Pereira, Oswaldo L. Ramos,Camilo Pimentel, Rubens Gagliardi, W.L. Sanvito, N. Lander and R. Mechoulam Departments de Psicobiologia, Departamento de Medicina, Departamento deNeurologia, Escola Paulista de Medicina; Departamento de Neurologia,Faculdade de Medicina da Santa Case, Sao Paulo, [Brazil] and Department ofNatural Products, Pharmacy School, Hebrew […]

Analysis of Online Forum Discussions on Cannabis Use and ADHD

This article originally appeared at https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156614 “I Use Weed for My ADHD”: A Qualitative Analysis of Online Forum Discussions on Cannabis Use and ADHD Background Attention-deficit/hyperactivity disorder (ADHD) is a risk factor for problematic cannabis use. However, clinical and anecdotal evidence suggest an increasingly popular perception that cannabis is therapeutic for ADHD, including via online […]

Clinical outcome analysis of patients with autism spectrum disorder

This article originally appeared at https://journals.sagepub.com/doi/full/10.1177/20451253221116240 Introduction: Cannabis-based medicinal products (CBMPs) have been identified as a promising novel therapeutic for symptoms and comorbidities related to autism spectrum disorder (ASD). However, there is a paucity of clinical evidence of their efficacy and safety. Objective: This case series aims to assess changes to health-related quality of life […]

Cognitive improvement following full-spectrum, high-cannabidiol treatment for anxiety

This article originally appeared at https://www.nature.com/articles/s43856-022-00202-8.epdf?sharing_token=SRm7cZn_w2Nek3b_ZAj-i9RgN0jAjWel9jnR3ZoTv0O1XXfjG2FzIlbbIYsF_ifjMu3OZ6uaWXAhcnDcKI0mLj_TdMOcTh76iHLqwXuySFzTIPfMaKNgkdrFQhxCsflmSg5iDB1C7__ByKoqrf_zDHJpXvEopmNmeUov2bk3M04%3D Clinical and cognitive improvement following full-spectrum, high-cannabidiol treatment for anxiety: open-label data from a two-stage, phase 2 clinical trial Authors: Mary Kathryn Dahlgren 1,2,3, Ashley M. Lambros1,2, Rosemary T. Smith1,2, Kelly A. Sagar1,2,3, Celine El-Abboud1,2 & Staci A. Gruber 1,2, Plain language summaryCannabidiol (CBD) is a compound found within […]

Medical cannabis in the treatment of treatment-resistant, chronic cluster headache. A retrospective report

This article originally appeared at https://www.researchgate.net/publication/274891934_EHMTI-0136_Medical_cannabis_in_the_treatment_of_treatment-resistant_chronic_cluster_headache_A_retrospective_report A Mosek*, M Dano, Y Fainmesser, Z HybloomFrom 4th European Headache and Migraine Trust International Congress: EHMTIC 2014Copenhagen, Denmark. 18-21 September 2014 Background Treatment-resistant chronic cluster headache is a debilitating disease. Since 2011 we were able to offer cannabis and we hereby report our experience using cannabis in this […]

Assessing the Tolerability of Two Different Ratios of Medicinal Cannabis in Patients With High Grade Gliomas

This originally appeared at https://www.frontiersin.org/articles/10.3389/fonc.2021.649555/full Authors: Janet Schloss1,2,3*, Judith Lacey4,5,6, Justin Sinclair4, Amie Steel3, Michael Sughrue7, David Sibbritt3 and Charles Teo7 Background: Cannabis for cancer is very topical and, given the use of illicit cannabis preparations used in this vulnerable population, research investigating standardised, quality-assured medicinal cannabis is critical to inform clinicians and assist patient […]

Cannabidiol’s neuroprotective properties and potential treatment of traumatic brain injuries

This article originally appeared at https://www.frontiersin.org/articles/10.3389/fneur.2023.1087011/full#.ZBW4f70oTuM.linkedin Cannabidiol (CBD) has numerous pharmacological targets that initiate anti-inflammatory, antioxidative, and antiepileptic properties. These neuroprotective benefits have generated interest in CBD’s therapeutic potential against the secondary injury cascade from traumatic brain injury (TBI). There are currently no effective broad treatment strategies for combating the damaging mechanisms that follow the […]

The Influence of Recency of Use on fMRI Response During Spatial Working Memory in Adolescent Marijuana Users

This originally appeared at https://pubmed.ncbi.nlm.nih.gov/21053763/ Abstract- Some neurocognitive recovery occurs within a month of abstinence from heavy marijuana use, yet functional magnetic resonance imaging (fMRI) has revealed altered activation among recent and abstinent adult users. We compared fMRl response during a spatial working memory (SWM) task between adolescent marijuana users with brief and sustained durations […]