Medical Marijuana Legalization and Opioid- and Pain-Related Outcomes Among Patients Newly Diagnosed With Cancer Receiving Anticancer Treatment

This article originally appeared at https://jamanetwork.com/journals/jamaoncology/article-abstract/2799132 Authors Yuhua Bao, PhD1,2; Hao Zhang, PhD1; Eduardo Bruera, MD3; et alRussell Portenoy, MD4,5,6; William E. Rosa, PhD, MBE, APRN7; M. Carrington Reid, MD, PhD8; Hefei Wen, PhD9 JAMA Oncol. 2023;9(2):206-214. doi:10.1001/jamaoncol.2022.5623 Key Points Question  Is medical marijuana legalization associated with opioid-related and pain-related outcomes for adult patients newly diagnosed with cancer and receiving anticancer treatment? Findings  This cross-sectional study of 38 189 patients […]

Medical Cannabis Patients Report Improvements in Health Functioning and Reductions in Opiate Use

This article originally appeared at https://www.tandfonline.com/doi/full/10.1080/10826084.2022.2107673 Abstract Purpose: Opioid use rates have dropped as North American patients gain access to medical cannabis, indicating a harm reduction role, yet health outcomes remain mostly unexplored. This study presents self-reported medical cannabis use, perceptions of health functioning, and changes in opioid pain medication use in Florida medical cannabis […]

Assessing the Impact of Marijuana Decriminalization on Vehicle Accident

This article originally appeared at https://www.cia-ica.ca/publications/publication-details/rp222163 This study proposes data-driven and reliable tools for assessing the impact of changes in marijuana laws on vehicle accident experience, by harnessing the publicly available data with the power of modern statistical and machine learning techniques under the integrative framework for impact analysis and uncertainty quantification. Executive summary This […]

Cannabis Is Exactly 114 Times Less Toxic Than Alcohol

This article originally appeared at https://www.leafly.com/news/science-tech/the-medical-minute-cannabis-is-exactly-114-times-less-toxic-than Research published in Scientific Reports rated recreational drugs according to their toxicity, and none of us blinked an eye when we saw cannabis sitting at the very bottom of the list. But maybe a few eyebrows were raised when the report awarded alcohol 1st place in the contest of […]

Comparative risk assessment of alcohol, tobacco, cannabis and other illicit drugs using the margin of exposure approach

This article originally appeared at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311234/ Abstract A comparative risk assessment of drugs including alcohol and tobacco using the margin of exposure (MOE) approach was conducted. The MOE is defined as ratio between toxicological threshold (benchmark dose) and estimated human intake. Median lethal dose values from animal experiments were used to derive the benchmark dose. […]

Minor Cannabinoid Therapeutic Uses

This article originally appeared at https://www.higherlearninglv.co/post/understanding-minor-cannabinoids Welcome to Cannabis Conclusions, a unique educational series from Higher Learning LV that is targeted at hemp and cannabis industry professionals. This series provides readers with the conclusion section from important modern peer-reviewed research studies. A November 2021 study entitled “Minor Cannabinoids: Biosynthesis, Molecular Pharmacology, and Potential Therapeutic Uses” […]

Cannabinoid Receptor-2 Ameliorates Inflammation in Crohn’s Disease

This article originally appeared at https://academic.oup.com/ecco-jcc/article/11/11/1369/3977952?login=false Abstract Background and Aims Cannabinoid receptor stimulation may have positive symptomatic effects on inflammatory bowel disease [IBD] patients through analgesic and anti-inflammatory effects. The cannabinoid 2 receptor [CB2R] is expressed primarily on immune cells, including CD4+ T cells, and is induced by active inflammation in both humans and mice. […]

How Do You Know if You’re Addicted to Weed?

This article originally appeared at https://www.nytimes.com/2023/04/10/well/mind/weed-addiction.html By Dana G. Smith Smoking weed had always been a social activity for Julian. He first tried cannabis in high school, and as an adult he would smoke a couple of times a month with friends. But things changed after he moved to a new city where he didn’t […]

Majority in Finland favour cannabis decriminalisation, THL survey finds

This article originally appeared at https://yle.fi/a/74-20027123 For the first time in the survey’s 30-year history, more people said they think that using cannabis regularly is not as risky as weekly binge drinking. The survey also found 29 percent of respondents saying they would be prepared to decriminalise all drug use, which is nine percentage points […]

How Thailand’s Deputy Prime Minister Pushed Through Asia’s First Cannabis Legalization

This article originally appeared at https://time.com/6273768/anutin-charnvirakul-interview-cannabis/ Until last summer, Thailand had some of the world’s harshest drug laws, with possession of cannabis then punishable by up to 15 years in prison. But on June 9, marijuana was decriminalized and a resurgent cannabis culture has seen dispensaries popping up across the Southeast Asian nation of 70 […]