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This article originally appeared at https://www.nature.com/articles/1210641 D9-Tetrahydrocannabinol (THC) is the primary cannabinoid of marijuana and has been shown to either potentiate or inhibit tumor growth, depending on the type of cancer and its pathogenesis. Little is known about the activity of cannabinoids like THC on epidermal growth factor receptor-overexpressing lung cancers, which are often highly…

This article originally appeared at https://www.marijuanamoment.net/medical-marijuana-legalization-linked-to-significant-decrease-in-opioid-related-payments-to-doctors-study-finds/ A new study is linking state-level medical marijuana legalization to reduced opioid payouts to doctors—another datapoint suggesting that patients use cannabis as an alternative to prescription drugs when given legal access. The study from researchers at the University of Florida, University of Southern California and Purdue University identified “a…

This article originally appeared at https://jamanetwork.com/journals/jamaoncology/article-abstract/2799132 Authors Yuhua Bao, PhD1,2; Hao Zhang, PhD1; Eduardo Bruera, MD3; et alRussell Portenoy, MD4,5,6; William E. Rosa, PhD, MBE, APRN7; M. Carrington Reid, MD, PhD8; Hefei Wen, PhD9 JAMA Oncol. 2023;9(2):206-214. doi:10.1001/jamaoncol.2022.5623 Key Points Question  Is medical marijuana legalization associated with opioid-related and pain-related outcomes for adult patients newly diagnosed with cancer and receiving anticancer treatment? Findings  This cross-sectional study of 38 189 patients…

This article originally appeared at https://www.tandfonline.com/doi/full/10.1080/10826084.2022.2107673 Abstract Purpose: Opioid use rates have dropped as North American patients gain access to medical cannabis, indicating a harm reduction role, yet health outcomes remain mostly unexplored. This study presents self-reported medical cannabis use, perceptions of health functioning, and changes in opioid pain medication use in Florida medical cannabis…

This article originally appeared at https://www.cia-ica.ca/publications/publication-details/rp222163 This study proposes data-driven and reliable tools for assessing the impact of changes in marijuana laws on vehicle accident experience, by harnessing the publicly available data with the power of modern statistical and machine learning techniques under the integrative framework for impact analysis and uncertainty quantification. Executive summary This…

This article originally appeared at https://www.leafly.com/news/science-tech/the-medical-minute-cannabis-is-exactly-114-times-less-toxic-than Research published in Scientific Reports rated recreational drugs according to their toxicity, and none of us blinked an eye when we saw cannabis sitting at the very bottom of the list. But maybe a few eyebrows were raised when the report awarded alcohol 1st place in the contest of…

This article originally appeared at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311234/ Abstract A comparative risk assessment of drugs including alcohol and tobacco using the margin of exposure (MOE) approach was conducted. The MOE is defined as ratio between toxicological threshold (benchmark dose) and estimated human intake. Median lethal dose values from animal experiments were used to derive the benchmark dose….

This article originally appeared at https://www.higherlearninglv.co/post/understanding-minor-cannabinoids Welcome to Cannabis Conclusions, a unique educational series from Higher Learning LV that is targeted at hemp and cannabis industry professionals. This series provides readers with the conclusion section from important modern peer-reviewed research studies. A November 2021 study entitled “Minor Cannabinoids: Biosynthesis, Molecular Pharmacology, and Potential Therapeutic Uses”…

This article originally appeared at https://academic.oup.com/ecco-jcc/article/11/11/1369/3977952?login=false Abstract Background and Aims Cannabinoid receptor stimulation may have positive symptomatic effects on inflammatory bowel disease [IBD] patients through analgesic and anti-inflammatory effects. The cannabinoid 2 receptor [CB2R] is expressed primarily on immune cells, including CD4+ T cells, and is induced by active inflammation in both humans and mice….

This article originally appeared at https://www.nytimes.com/2023/04/10/well/mind/weed-addiction.html By Dana G. Smith Smoking weed had always been a social activity for Julian. He first tried cannabis in high school, and as an adult he would smoke a couple of times a month with friends. But things changed after he moved to a new city where he didn’t…