The effects of dronabinol during detoxification and the initiation of treatment with extended release naltrexone
PMID: 26187456 PMCID: PMC4536087 DOI: 10.1016/j.drugalcdep.2015.05.013 Abstract Background: Evidence suggests that the cannabinoid system is involved in the maintenance of opioid dependence. We examined whether dronabinol, a cannabinoid receptor type 1 partial agonist, reduces opioid withdrawal and increases retention in treatment with extended release naltrexone (XR-naltrexone). Methods: Opioid dependent participants were randomized to receive dronabinol…