A Longitudinal Comparison of Persistent Cannabis vs Tobacco Users
This article originally appeared at https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2526003 Associations Between Cannabis Use and Physical Health Problems in Early Midlife A Longitudinal Comparison of Persistent Cannabis vs Tobacco Users Madeline H. Meier, PhD1; Avshalom Caspi, PhD2,3,4; Magdalena Cerdá, DrPH5; et alRobert J. Hancox, MD6; HonaLee Harrington, BA2,3; Renate Houts, PhD2,3; Richie Poulton, PhD7; Sandhya Ramrakha, PhD7; W. Murray Thomson, PhD8; Terrie E. Moffitt, PhD2,3,4 JAMA Psychiatry. 2016;73(7):731-740. doi:10.1001/jamapsychiatry.2016.0637 Abstract Importance After major policy changes in the United States, policymakers, health care professionals, and the general public seek information about […]
Is Marijuana Really a Gateway Drug?
This article originally appeared at https://www.discovermagazine.com/mind/is-marijuana-really-a-gateway-drug Chris Christie recently said that marijuana is a “gateway drug” while arguing for enforcement of its federal status as an illegal substance. Though there are correlations between marijuana use and other drugs, there is no conclusive evidence that one actually causes the other. The science on this topic is far from […]
Marijuana Could Help Reduce Depression and Anxiety
This article originally appeared at https://www.discovermagazine.com/health/tracing-the-link-between-marijuana-and-mental-health Our knowledge about (and acceptance of) cannabis has expanded rapidly in recent years. But researchers are still probing the link between weed, depression and other mental health markers. There was a panic over pot in the 1930s. When the movie Reefer Madness came out in 1936, the criminalization of marijuana was […]
Marijuana Could Be Key in Curing Alzheimer’s Disease
This article originally appeared at https://bigthink.com/health/marijuana-may-be-key-in-curing-alzheimers-find-researchers/ Researchers find that a compound within marijuana may potentially protect from the onset of Alzheimer’s disease. In news that might be counterintuitive to the common experience of how weed affects memory, researchers have shown that marijuana could have potential in treating Alzheimer’s disease. In particular, scientists from Salk Institute in […]
A Guide to Marijuana Legalization in the US
This article originally appeared at https://www.usnews.com/news/best-states/articles/where-is-marijuana-legal-a-guide-to-marijuana-legalization Twenty-two states – along with Washington, D.C. and Guam – have acted to legalize recreational Cannabis On Election Day in 2012, voters in Colorado and Washington approved ballot measures to legalize the recreational use and sale of cannabis, making the states the first in the U.S. to do so. […]
Alcohol and Other Substance Use Before and During the COVID-19 Pandemic Among High School Students
This article originally appeared at https://www.cdc.gov/mmwr/volumes/72/su/su7201a10.htm Authors: Brooke E. Hoots, PhD1; Jingjing Li, PhD, MD2; Marci Feldman Hertz, MS2; Marissa B. Esser, PhD3; Adriana Rico, MPH2; Evelyn Y. Zavala, MPH2; Christopher M. Jones, PharmD, DrPH4 Abstract Adolescence is a critical phase of development and is frequently a period of initiating and engaging in risky behaviors, […]
State Cannabis Legalization and Psychosis-Related Health Care Utilization
This article originally appeared at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925044/ Published online 2023 Jan 25. doi: 10.1001/jamanetworkopen.2022.52689 PMCID: PMC9925044 NIHMSID: NIHMS1869192 PMID: 36696111 Authors: Holly Elser, MD, PhD, 1 , 2 Keith Humphreys, PhD, 3 , 4 Mathew V. Kiang, ScD, 5 Swapnil Mehta, MD, 4 Jong H. Yoon, MD, 4 , 6 William O. Faustman, PhD, 4 , 6 […]
Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma
This article originally appeared at https://jpet.aspetjournals.org/content/318/3/1375 Authors: Alessia Ligresti, Aniello Schiano Moriello, Katarzyna Starowicz, Isabel Matias, Simona Pisanti, Luciano De Petrocellis, Chiara Laezza, Giuseppe Portella, Maurizio Bifulco and Vincenzo Di Marzo Journal of Pharmacology and Experimental Therapeutics September 2006, 318 (3) 1375-1387; DOI: https://doi.org/10.1124/jpet.106.105247
Cannabidiol Enhances Intestinal Cannabinoid Receptor Type 2 Receptor Expression and Activation Increasing Regulatory T Cells and Reduces Murine Acute Graft-versus-Host Disease without Interfering with the Graft-versus-Leukemia Response
This article originally appeared at https://jpet.aspetjournals.org/content/377/2/273 Authors: Bárbara Betônico Berg, Jaqueline Silva Soares, Isabela Ribeiro Paiva, Barbara Maximino Rezende, Milene Alvarenga Rachid, Stêfany Bruno de Assis Cau, Thiago Roberto Lima Romero, Vanessa Pinho, Mauro Martins Teixeira and Marina Gomes Miranda e Castor Journal of Pharmacology and Experimental Therapeutics May 2021, 377 (2) 273-283; DOI: https://doi.org/10.1124/jpet.120.000479 Abstract Cannabidiol (CBD) is a highly lipidic phytocannabinoid with remarkable anti-inflammatory effects. The aim of […]
The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells
This article originally appeared at https://gut.bmj.com/content/54/12/1741.abstract Authors: Abstract Background and aims: Cyclooxygenase 2 (COX-2) is upregulated in most colorectal cancers and is responsible for metabolism of the endogenous cannabinoid, anandamide, into prostaglandin-ethanolamides (PG-EAs). The aims of this study were to determine whether anandamide and PG-EAs induce cell death in colorectal carcinoma (CRC) cells, and whether high […]
