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Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1

This originally appeared at By: Robert Ramer,* Katharina Bublitz,* Nadine Freimuth,* Jutta Merkord,* Helga Rohde,* Maria Haustein,* Philipp Borchert,* Ellen Schmuhl,* Michael Linnebacher,† and Burkhard Hinz*,1*Institute of Toxicology and Pharmacology and †Section of Molecular Oncology and Immunotherapy, Department of General Surgery, University of Rostock, Rostock, Germany ABSTRACT Cannabinoids inhibit cancer cell invasion via increasing […]

Turning Over a New Leaf: Cannabinoid and Endocannabinoid Modulation of Immune Function

Abstract Cannabis is a complex substance that harbors terpenoid-like compounds referred to as phytocannabinoids. The major psychoactive phytocannabinoid found in cannabis Δ9-tetrahydrocannabinol (THC) produces the majority of its pharmacological effects through two cannabinoid receptors, termed CB1 and CB2. The discovery of these receptors as linked functionally to distinct biological effects of THC, and the subsequent […]