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An Evidence Based Review of Acute and Long-Term Effects of Cannabis Use on Executive Cognitive Functions

This originally appeared at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037578/#R45 Abstract Cannabis use has been shown to impair cognitive functions on a number of levels—from basic motor coordination to more complex executive function tasks, such as the ability to plan, organize, solve problems, make decisions, remember, and control emotions and behavior. These deficits differ in severity depending on the quantity, […]

Cannabinoids: a new hope for breast cancer therapy?

This originally appeared at https://pubmed.ncbi.nlm.nih.gov/22776349/ a b s t r a c tBreast cancer is a very common disease that affects approximately 1 in 10 women at some point in theirlives. Importantly, breast cancer cannot be considered a single disease as it is characterized by distinctpathological and molecular subtypes that are treated with different therapies […]

Cannabis and Cannabinoids for Cancer Health Professionals

This originally appeared at https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq#section/all from the US institutes on Cancer Overview This cancer information summary provides an overview of the use of Cannabis and its components as a treatment for people with cancer-related symptoms caused by the disease itself or its treatment. This summary contains the following key information: Many of the medical and […]

Cannabinoids for the Treatment of Chronic Non-Cancer Pain: An Updated Systematic Review of Randomized Controlled Trials

This originally appeared at https://pubmed.ncbi.nlm.nih.gov/25796592/ Abstract An updated systematic review of randomized con-trolled trials examining cannabinoids in the treatment ofchronic non-cancer pain was conducted according to PRISMA guidelines for systematic reviews reporting on health careoutcomes. Eleven trials published since our last review metinclusion criteria. The quality of the trials was excellent. Sev-en of the trials […]

Studies Showing an Anti-Cancer Effect

This is a mirror of the page at http://safeaccess.ca/research/cancer.htm A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma Caihua Liang,1 Michael D. McClean,3 Carmen Marsit,2 Brock Christensen,1,2 Edward Peters,4 Heather H. Nelson5 and Karl T. Kelsey1,2Cannabinoids, constituents of marijuana smoke, have been recognized to have potential antitumor properties. However, the […]

Research Suggests CBD’s Anxiety Relief Is Due To Neurogenesis

This article originally appeared at https://academic.oup.com/ijnp/article/16/6/1407/754216?login=false The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system Alline C. Campos, Zaira Ortega, Javier Palazuelos, Manoela V. Fogaça, Daniele C. Aguiar, Javier Díaz-Alonso, Silvia Ortega-Gutiérrez, Henar Vázquez-Villa, Fabricio A. Moreira, Manuel Guzmán … Show more International Journal of Neuropsychopharmacology, […]

Long-term behavioral and biochemical effects of an ultra-low dose of D9-tetrahydrocannabinol (THC) neuroprotection and ERK signaling

This article originally appeared at https://link.springer.com/article/10.1007/s00221-012-3186-5 Abstract We have previously reported that a singleinjection of an ultra-low dose of delta-9-tetrahydrocanna-binol (THC; the psychoactive ingredient of marijuana)protected the brain from pentylenentetrazole (PTZ)-induced cognitive deficits when applied 1–7 days before or1–3 days after the insult. In the present study we expandedthe protective profile of THC by showing […]

Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects

This originally appeared at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253627/ Abstract The hippocampal dentate gyrus in the adult mammalian brain contains neural stem/progenitor cells (NS/PCs) capable of generating new neurons, i.e., neurogenesis. Most drugs of abuse examined to date decrease adult hippocampal neurogenesis, but the effects of cannabis (marijuana or cannabinoids) on hippocampal neurogenesis remain unknown. This study aimed at […]

Overview of the Endocannabinoid system.

Medicinal cannabis is routinely recommended for a wide variety of conditions. For example, in California, patients can qualify for cannabis medicine if they have AIDS, anorexia, arthritis, cachexia, cancer, chronic pain, glaucoma, migraines, muscle spasms, seizures, nausea, or other chronic symptoms. This begs the question – how can cannabis be recommended for so many different […]