Marijuana Could Help Reduce Depression and Anxiety
This article originally appeared at https://www.discovermagazine.com/health/tracing-the-link-between-marijuana-and-mental-health Our knowledge about (and acceptance of) cannabis has expanded rapidly in recent years. But researchers are still probing the link between weed, depression and other mental health markers. There was a panic over pot in the 1930s. When the movie Reefer Madness came out in 1936, the criminalization of marijuana was […]
Marijuana Could Be Key in Curing Alzheimer’s Disease
This article originally appeared at https://bigthink.com/health/marijuana-may-be-key-in-curing-alzheimers-find-researchers/ Researchers find that a compound within marijuana may potentially protect from the onset of Alzheimer’s disease. In news that might be counterintuitive to the common experience of how weed affects memory, researchers have shown that marijuana could have potential in treating Alzheimer’s disease. In particular, scientists from Salk Institute in […]
A Guide to Marijuana Legalization in the US
This article originally appeared at https://www.usnews.com/news/best-states/articles/where-is-marijuana-legal-a-guide-to-marijuana-legalization Twenty-two states – along with Washington, D.C. and Guam – have acted to legalize recreational Cannabis On Election Day in 2012, voters in Colorado and Washington approved ballot measures to legalize the recreational use and sale of cannabis, making the states the first in the U.S. to do so. […]
Alcohol and Other Substance Use Before and During the COVID-19 Pandemic Among High School Students
This article originally appeared at https://www.cdc.gov/mmwr/volumes/72/su/su7201a10.htm Authors: Brooke E. Hoots, PhD1; Jingjing Li, PhD, MD2; Marci Feldman Hertz, MS2; Marissa B. Esser, PhD3; Adriana Rico, MPH2; Evelyn Y. Zavala, MPH2; Christopher M. Jones, PharmD, DrPH4 Abstract Adolescence is a critical phase of development and is frequently a period of initiating and engaging in risky behaviors, […]
State Cannabis Legalization and Psychosis-Related Health Care Utilization
This article originally appeared at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925044/ Published online 2023 Jan 25. doi: 10.1001/jamanetworkopen.2022.52689 PMCID: PMC9925044 NIHMSID: NIHMS1869192 PMID: 36696111 Authors: Holly Elser, MD, PhD, 1 , 2 Keith Humphreys, PhD, 3 , 4 Mathew V. Kiang, ScD, 5 Swapnil Mehta, MD, 4 Jong H. Yoon, MD, 4 , 6 William O. Faustman, PhD, 4 , 6 […]
Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma
This article originally appeared at https://jpet.aspetjournals.org/content/318/3/1375 Authors: Alessia Ligresti, Aniello Schiano Moriello, Katarzyna Starowicz, Isabel Matias, Simona Pisanti, Luciano De Petrocellis, Chiara Laezza, Giuseppe Portella, Maurizio Bifulco and Vincenzo Di Marzo Journal of Pharmacology and Experimental Therapeutics September 2006, 318 (3) 1375-1387; DOI: https://doi.org/10.1124/jpet.106.105247
Cannabidiol Enhances Intestinal Cannabinoid Receptor Type 2 Receptor Expression and Activation Increasing Regulatory T Cells and Reduces Murine Acute Graft-versus-Host Disease without Interfering with the Graft-versus-Leukemia Response
This article originally appeared at https://jpet.aspetjournals.org/content/377/2/273 Authors: Bárbara Betônico Berg, Jaqueline Silva Soares, Isabela Ribeiro Paiva, Barbara Maximino Rezende, Milene Alvarenga Rachid, Stêfany Bruno de Assis Cau, Thiago Roberto Lima Romero, Vanessa Pinho, Mauro Martins Teixeira and Marina Gomes Miranda e Castor Journal of Pharmacology and Experimental Therapeutics May 2021, 377 (2) 273-283; DOI: https://doi.org/10.1124/jpet.120.000479 Abstract Cannabidiol (CBD) is a highly lipidic phytocannabinoid with remarkable anti-inflammatory effects. The aim of […]
The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells
This article originally appeared at https://gut.bmj.com/content/54/12/1741.abstract Authors: Abstract Background and aims: Cyclooxygenase 2 (COX-2) is upregulated in most colorectal cancers and is responsible for metabolism of the endogenous cannabinoid, anandamide, into prostaglandin-ethanolamides (PG-EAs). The aims of this study were to determine whether anandamide and PG-EAs induce cell death in colorectal carcinoma (CRC) cells, and whether high […]
The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation
This article originally appeared at https://www.pnas.org/doi/abs/10.1073/pnas.95.14.8375 Authors: Luciano De Petrocellis, Dominique Melck, Antonella Palmisano, +3, and Vincenzo Di MarzoAuthors Info & Affiliations July 7, 1998 https://doi.org/10.1073/pnas.95.14.8375 Abstract Anandamide was the first brain metabolite shown to act as a ligand of “central” CB1 cannabinoid receptors. Here we report that the endogenous cannabinoid potently and selectively inhibits the proliferation of human breast cancer cells in vitro. […]
Prevention of Alzheimer’s Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation
This article originally appeared at https://www.jneurosci.org/content/25/8/1904.abstract Authors: Belén G. Ramírez, Cristina Blázquez, Teresa Gómez del Pulgar, Manuel Guzmán and María L. de Ceballos Journal of Neuroscience 23 February 2005, 25 (8) 1904-1913; DOI: https://doi.org/10.1523/JNEUROSCI.4540-04.2005 Abstract Alzheimer’s disease (AD) is characterized by enhanced β-amyloid peptide (βA) deposition along with glial activation in senile plaques, selective neuronal loss, and cognitive deficits. Cannabinoids are neuroprotective agents against excitotoxicity in […]
