Assessing the Tolerability of Two Different Ratios of Medicinal Cannabis in Patients With High Grade Gliomas

This originally appeared at https://www.frontiersin.org/articles/10.3389/fonc.2021.649555/full Authors: Janet Schloss1,2,3*, Judith Lacey4,5,6, Justin Sinclair4, Amie Steel3, Michael Sughrue7, David Sibbritt3 and Charles Teo7 Background: Cannabis for cancer is very topical and, given the use of illicit cannabis preparations used in this vulnerable population, research investigating standardised, quality-assured medicinal cannabis is critical to inform clinicians and assist patient […]

Cannabidiol and periodontal inflammatory disease: A critical assessment of Cannabis for dental pain

This article originally appeared at https://pubmed.ncbi.nlm.nih.gov/35332345/ Authors: Petr Jirasek  1 , Alexandr Jusku  1 , Vilim Simanek  2 , Jana Frankova  2 , Jan Storch  3 , Jan Vacek  2 PMID: 35332345 DOI: 10.5507/bp.2022.012 Cannabidiol (CBD), a non-psychotropic cannabinoid produced by the genus Cannabis, is a phytoceutical that activates the endocannabinoid system (ECS) through binding to CB1 and CB2 receptors. […]

Can Medical Cannabis or CBD help with Perimenopause-and Menopausal related issues?

This article originally appeared at https://www.truenorthlabs.ch/news/can-medical-cannabis-or-cbd-help-with-perimenopause-and-menopausal-related-issues According to the British Menopause Society, 75% of women are affected by menopausal symptoms – an estimated 1.1 billion worldwide. Until recently, hormone replacement therapy (HRT) was the go-to treatment for menopause, however studies in recent years have shown a steep decline in its use (46% in the USA, […]

Does Cannabis Affect Men and Women Differently? Exploring the Impact of Hormones

This article originally appeared at https://www.truenorthlabs.ch/news/does-cannabis-affect-men-and-women-differently-exploring-the-impact-of-hormones The impact of hormones on the effects of cannabis can be complex and often misunderstood. While past studies have indicated that the effects of cannabis are the same for men and women, there is a growing body of evidence to suggest that hormonal fluctuations throughout the month can have […]

Cannabidiol’s neuroprotective properties and potential treatment of traumatic brain injuries

This article originally appeared at https://www.frontiersin.org/articles/10.3389/fneur.2023.1087011/full#.ZBW4f70oTuM.linkedin Cannabidiol (CBD) has numerous pharmacological targets that initiate anti-inflammatory, antioxidative, and antiepileptic properties. These neuroprotective benefits have generated interest in CBD’s therapeutic potential against the secondary injury cascade from traumatic brain injury (TBI). There are currently no effective broad treatment strategies for combating the damaging mechanisms that follow the […]

Delta9-Tetrahydrocannabinol inhibits lung cancer cell migration in vitro as well as its growth and metastasis

This article originally appeared at https://www.nature.com/articles/1210641 D9-Tetrahydrocannabinol (THC) is the primary cannabinoid of marijuana and has been shown to either potentiate or inhibit tumor growth, depending on the type of cancer and its pathogenesis. Little is known about the activity of cannabinoids like THC on epidermal growth factor receptor-overexpressing lung cancers, which are often highly […]

Medical Marijuana Legalization Linked To ‘Significant Decrease’ In Opioid-Related Payments To Doctors, Study Finds

This article originally appeared at https://www.marijuanamoment.net/medical-marijuana-legalization-linked-to-significant-decrease-in-opioid-related-payments-to-doctors-study-finds/ A new study is linking state-level medical marijuana legalization to reduced opioid payouts to doctors—another datapoint suggesting that patients use cannabis as an alternative to prescription drugs when given legal access. The study from researchers at the University of Florida, University of Southern California and Purdue University identified “a […]

Medical Marijuana Legalization and Opioid- and Pain-Related Outcomes Among Patients Newly Diagnosed With Cancer Receiving Anticancer Treatment

This article originally appeared at https://jamanetwork.com/journals/jamaoncology/article-abstract/2799132 Authors Yuhua Bao, PhD1,2; Hao Zhang, PhD1; Eduardo Bruera, MD3; et alRussell Portenoy, MD4,5,6; William E. Rosa, PhD, MBE, APRN7; M. Carrington Reid, MD, PhD8; Hefei Wen, PhD9 JAMA Oncol. 2023;9(2):206-214. doi:10.1001/jamaoncol.2022.5623 Key Points Question  Is medical marijuana legalization associated with opioid-related and pain-related outcomes for adult patients newly diagnosed with cancer and receiving anticancer treatment? Findings  This cross-sectional study of 38 189 patients […]

Medical Cannabis Patients Report Improvements in Health Functioning and Reductions in Opiate Use

This article originally appeared at https://www.tandfonline.com/doi/full/10.1080/10826084.2022.2107673 Abstract Purpose: Opioid use rates have dropped as North American patients gain access to medical cannabis, indicating a harm reduction role, yet health outcomes remain mostly unexplored. This study presents self-reported medical cannabis use, perceptions of health functioning, and changes in opioid pain medication use in Florida medical cannabis […]

Assessing the Impact of Marijuana Decriminalization on Vehicle Accident

This article originally appeared at https://www.cia-ica.ca/publications/publication-details/rp222163 This study proposes data-driven and reliable tools for assessing the impact of changes in marijuana laws on vehicle accident experience, by harnessing the publicly available data with the power of modern statistical and machine learning techniques under the integrative framework for impact analysis and uncertainty quantification. Executive summary This […]