Abstract Traumatic brain injury (TBI) is associated with significant morbidity and mortality. Several studies have demonstrated neuroprotective effects of cannabinoids. The objective of this study was to establish a relationship between the presence of a positive toxicology screen for tetrahydrocannabinol (THC) and mortality after TBI. A 3-year retrospective review of registry data at a Level…
ABSTRACT Chronic neuropathic pain is often refractory to standard pharmacological treatments. Although growing evidence supports the use of inhaled cannabis for neuropathic pain, the lack of standard inhaled dosing plays a major obstacle in cannabis becoming a “main stream” pharmacological treatment for neuropathic pain. The objective of this study was to explore the pharmacokinetics, safety,…
Abstract The hippocampal dentate gyrus in the adult mammalian brain contains neural stem/progenitor cells (NS/PCs) capable of generating new neurons, i.e., neurogenesis. Most drugs of abuse examined to date decrease adult hippocampal neurogenesis, but the effects of cannabis (marijuana or cannabinoids) on hippocampal neurogenesis remain unknown. This study aimed at investigating the potential regulatory capacity…
A 2012 Duke University study made international headlines when it purported to find a link between heavy marijuana use and IQ decline among teenagers. Other researchers questioned the findings almost immediately: Columbia University’s Carl Hart noted the very small sample of heavy users (38) in the study, leading him to question how generalizable the results…
This article originally appeared at https://www.fastcompany.com/3021612/secrets-of-the-most-productive-pothead-doug-benson Stand-up comedian Doug Benson has released a comedy album every year for the past six years, hosts several podcasts (including The Benson Interruption), tours constantly, and makes films and TV shows. Oh, and he manages to do all of this while completely baked. Fast Company: Are you high right…
Laura Weinkle M.S. , Christopher H. Domen Ph.D. , Ian Shelton B.A. ,Stefan Sillau Ph.D. , Kavita Nair Ph.D. , Enrique Alvarez M.D., Ph.D. , Exploring cannabis use by pa-tients with multiple sclerosis in a state where cannabis is legal, Multiple Sclerosis and Related Disorders(2018), doi: https://doi.org/10.1016/j.msard.2018.11.022 Highlights: 38% percent of Multiple Sclerosis patients surveyed…
PMID: 29059132 DOI: 10.1097/WNF.0000000000000246 Abstract Background: The use of medical cannabis (MC) is controversial. Support for its benefits is based on small clinical series. Objective: The aim of this study was to report the results of a standardized interview study that retrospectively assessed the effects of MC on symptoms of Parkinson disease (PD) and its…
Abstract The prevalence of marijuana abuse and dependence disorders has been increasing among adults and adolescents in the United States. This paper reviews the problems associated with marijuana use, including unique characteristics of marijuana dependence, and the results of laboratory research and treatment trials to date. It also discusses limitations of current knowledge and potential…
SAN RAFAEL, Calif. — For as long as most residents can remember, smoking marijuana has been a part of life here. The fact that California legalized the practice in January went practically unnoticed in this quiet town a half-hour’s drive north of San Francisco, where some say the normalization of America’s marijuana culture got its…
There are real concerns with marijuana addiction. That doesn’t mean legalization is a bad idea. It is now widely accepted that marijuana is, at the very least, less dangerous than other recreational drugs. The typical line you’ll hear — I certainly do in my email inbox — is that “marijuana is harmless,” often meant as…
