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Marijuana Dependence and Its Treatment
ByOSadmin
Abstract The prevalence of marijuana abuse and dependence disorders has been increasing among adults and adolescents in the United States. This paper reviews the problems associated with marijuana use, including unique characteristics of marijuana dependence, and the results of laboratory research and treatment trials to date. It also discusses limitations of current knowledge and potential…
The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells
ByOSadmin
This article originally appeared at https://gut.bmj.com/content/54/12/1741.abstract Authors: Abstract Background and aims: Cyclooxygenase 2 (COX-2) is upregulated in most colorectal cancers and is responsible for metabolism of the endogenous cannabinoid, anandamide, into prostaglandin-ethanolamides (PG-EAs). The aims of this study were to determine whether anandamide and PG-EAs induce cell death in colorectal carcinoma (CRC) cells, and whether high…
Medical Cannabis Laws and Opioid Analgesic Overdose Mortality in the United States, 1999-2010
ByOSadmin
This originally appeared at https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1898878 October 2014 Marcus A. Bachhuber, MD1,2,3; Brendan Saloner, PhD3,4; Chinazo O. Cunningham, MD, MS5; et alColleen L. Barry, PhD, MPP3,6 JAMA Intern Med. 2014;174(10):1668-1673. doi:10.1001/jamainternmed.2014.4005 Abstract Importance Opioid analgesic overdose mortality continues to rise in the United States, driven by increases in prescribing for chronic pain. Because chronic pain is a major indication for medical cannabis, laws that establish access to medical cannabis may…
State Marijuana Laws and Traffic Fatalities
ByOSadmin
This originally appeared at https://rrs.scholasticahq.com/article/30970-state-marijuana-laws-and-traffic-fatalities Jim Dewey, Kristopher Kindle, Sravani Vadlamani, Reinaldo Sanchez-Arias Abstract: We examine the relationship between traffic fatalities and state marijuana laws using data from 1985 through 2019 and Poisson difference in difference models that allow effects to vary over time. We show numerous attributes of state marijuana laws are captured by…
State Cannabis Legalization and Psychosis-Related Health Care Utilization
ByOSadmin
This article originally appeared at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925044/ Published online 2023 Jan 25. doi: 10.1001/jamanetworkopen.2022.52689 PMCID: PMC9925044 NIHMSID: NIHMS1869192 PMID: 36696111 Authors: Holly Elser, MD, PhD, 1 , 2 Keith Humphreys, PhD, 3 , 4 Mathew V. Kiang, ScD, 5 Swapnil Mehta, MD, 4 Jong H. Yoon, MD, 4 , 6 William O. Faustman, PhD, 4 , 6…
This Is Your Brain While Videogaming Turkey legalises controlled cannabis production in 19 provinces
ByOSadmin
New government regulations will allow highly-controlled and ministry-sanctioned cannabis production in selected provinces for medical and scientific purposes Turkey has legalised cannabis production in 19 provinces in order to crack down on illegal production, according to new regulations by The Ministry of Food, Agriculture and Livestock. Published in the Official Gazette in late September, “Hemp…
